Download original University of Benin (UNIBEN) Physiology Past Questions and Answers below for your practice. We discovered 194 repeated questions from 2007 to 2015. Read it below and download your complete copy now.
This includes past MCQs in physiology exams administered to students of the following departments in the UI college of medicine
- Biochemistry/Medical Biochemistry
- Dentistry And Dental Surgery
- Medicine and Surgery
- Nursing / Nursing Science
- Optometry
- Pharmacy
- Physiology
1. The Golgi apparatus is
A. Found in all eukaryotic cells.
B. A collection of complex tubules and vesicles
C. Well developed in cells with secretory activity
D. Associated with endoplasmic reticulum
E. Not conspicuous in neurons
REVISION NOTES
A. True – Usually close to the nucleus
B. False – It is a collection of about six flattened, membrane-enclosed sacs stacked together.
C. True – Secretions are packaged into vesicles in the Golgi apparatus.
D. True – Proteins formed by the granular endoplasmic reticulum fuse with the membranes of the Golgi sacs before being packed into vesicles and released into the cytoplasm.
E. False – Neurons are secretory cells.
2. Exercise which doubles the metabolic rate is likely to at least double the
A. Oxygen consumption
B. Cardiac output
C. Stroke volume
D. Arterial PCO2
E. Minute volume
REVISION NOTES
A. True – Oxygen consumption is directly related to metabolic rate.
B. False – This rises more slowly than metabolic rate because tissue O2 extraction increases.
C. False – Since heart rate rises, stroke volume does not rise in proportion to metabolic rate.
D. False – This is little changed.
E. True – This rises proportionately more than metabolic rate.
3. Lymphocytes
A. Constitute 1–2 per cent of circulating white cells.
B. Are motile.
C. Can transform into plasma cells
D. Decrease in number following removal of the adult thymus gland.
E. Decrease in number during immunosuppressive drug therapy.
REVISION NOTES
A. False – About 20 per cent of leukocytes are lymphocytes.
B. True – They migrate by amoeboid movement to areas of chronic inflammation.
C. True – As plasma cells they manufacture humoral antibodies.
D. False – The thymus is atrophied and has little function in the adult.
E. True – Lymphocytes and immune responses are closely linked
4. Local metabolic activity is the chief factor determining the rate of blood flow to the
a. Heart
b. Skin
c. Skeletal muscle
d. Lung
e. Kidney
REVISION NOTES:
A. True – There is a close relationship between the work of the heart and coronary flow.
B. False – Skin blood flow is geared mainly to thermoregulation and normally exceeds that needed for skin’s modest metabolic requirements.
C. True – Local blood flow is largely determined by the vasoactive metabolites such as rising PCO2, H concentration and falling PO2. The changes produced by vasomotor nerves are small compared with those produced by metabolites.
D. False – The entire cardiac output must pass through the lungs regardless of the local metabolic needs of the pulmonary tissues. It is greatly in excess of the lungs’ metabolic needs.
E. False – As in skin, renal blood flow (about one quarter of total cardiac output) greatly exceeds local metabolic needs. The blood is sent to the kidneys for processing.
5. When secretory activity in the thyroid gland increases
A. The gland takes up iodide from the blood at a faster rate.
B. Its follicles enlarge and fill with colloid.
C. The follicular cells become more columnar.
D. The follicular cells ingest colloid by endocytosis.
E. The blood level of thyrotropin (TSH) increases.
REVISION NOTES
A. True – Iodide uptake is an index of activity.
B. False – The follicles shrink as the colloid content falls.
C. True – They change from cuboidal to columnar as their activity increases.
D. True – Reabsorption lacunae form as thyroglobulin is broken down to release hormones.
E. False – Negative feedback causes TSH levels to fall.
6. Which of the following processes are likely to be enhanced shortly after waking up? Select all that apply.
a) Growth hormone secretion
b) Glycogenesis
c) Lipolysis
d) Cortisol secretion
ANSWERS
a) Growth hormone secretion
c) Lipolysis
d) Cortisol secretion
REVISION NOTES
A night’s sleep represents a short period of fasting. In fasting, hyperglycaemic hormones, particularly GH and cortisol are secreted. There is an increase in the utilization of fats (lipolysis). Glycogenesis will only be stimulated once a meal has been eaten and plasma glucose levels have started to rise.
7. A raised blood pH and bicarbonate level is consistent with
A. Metabolic acidosis
B. Partly compensated respiratory alkalosis
C. A reduced PCO2
D. Chronic renal failure with a raised PCO2
E. A history of persistent vomiting of gastric contents
REVISION NOTES
A. False – It is consistent with a metabolic alkalosis.
B. False – A partly compensated acidosis has a low pH.
C. False – PCO2 is normally raised in metabolic alkalosis as a compensatory mechanism.
D. False – All these values are reduced in chronic renal failure.
E. True – Pyloric obstruction causes a metabolic alkalosis.
8. After a child is born
A. Its haemoglobin level rises steadily during the first year.
B. There should be a delay in clamping the umbilical cord so that blood from the placenta can drain into the fetus.
C. It should increase its weight by 10 per cent at four months.
D. Its brain can tolerate a lower blood glucose level than that of an adult.
E. Its brain can tolerate a lower oxygen level than that of an adult.
REVISION NOTES
A. False – It falls from around 170–200 g/liter to around 110 g/liter.
B. True – The placenta contains about half as much blood as the fetus; some can be transferred by uterine contraction.
C. False – Its weight should be doubled at this stage and trebled at one year.
D. True – It can tolerate about 25 per cent of the normal adult fasting level.
E. True – Fetal tissues are adapted to survive moderate hypoxia.
9. The tympanic membrane
A. Modifies the frequencies of sound waves impinging on the ear.
B. Stops vibrating almost immediately after the sound stops.
C. Bulges outwards when the pharyngotympanic tube is blocked.
D. Transmits sound more effectively when the small muscles of the middle ear are contracted.
E. Cannot transmit sound waves if it is perforated
REVISION NOTES
A. False – It faithfully reproduces the frequencies.
B. True – It is very nearly ‘critically damped’.
C. False – It bulges inwards as middle ear air is absorbed.
D. False – Reflex contraction of these muscles protects by damping vibration transmission
E. False – Small perforations cause about 5 decibels loss; complete destruction about 50
INCOMPLETE!!! INCOMPLETE!!! INCOMPLETE!!!
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