OAU Physiology MCQs Past Questions And Answers

Download original Obafemi Awolowo University (OAU) Physiology Past Questions and Answers below for your practice. We discovered 194 repeated questions from 2007 to 2023. Read it below and download your complete copy now.

This product contains past MCQs in physiology exams administered to students of the following departments in the UNILAG College of medicine

  1. Biochemistry
  2. Dentistry And Dental Surgery
  3. Medicine and Surgery
  4. Nursing / Nursing Science
  5. Pharmacy

1. Drinking a liter of water
A. Increases secretion of antidiuretic hormone
B. Reduces the plasma sodium concentration
C. Causes more osmolar change in portal venous than in systemic venous blood
D. Causes body cells to shrink
E. Decreases the specific gravity of the body
A. False – It suppresses secretion of antidiuretic hormone.
B. True – Osmolality is reduced in all the body fluid compartments.
C. True – The water is absorbed via the portal vein.
D. False – They swell as water is drawn in osmotically.
E. False – It moves it upwards from its value of less than 1.0.

2. Jejunal mucosal cells are similar to proximal convoluted tubular cells in that both
A. Absorb glucose by a process linked with sodium absorption.
B. Absorb chloride ions actively.
C. Absorb amino acids actively.
D. Are rich in mitochondria.
E. Possess microvilli on their luminal border.
A. True – In both cases, glucose absorption is blocked by phlorhizin.
B. False – In both, these follow passively the absorption of sodium.
C. True – Again the process requires active absorption of sodium.
D. True – Both expend considerable energy.
E. True – The two types of cell have very similar functions.

3. Circulating red blood cells
A. Are about 1 per cent nucleated.
B. May show an intracellular network pattern if appropriately stained.
C. Are distributed evenly across the blood stream in large blood vessels.
D. Travel at slower velocity in venules than in capillaries.
E. Deform as they pass through the capillaries.
A. False – Nucleated red cells are not normally seen in peripheral blood.
B. True – Reticulocytes, the most immature circulating RBCs, show this pattern when stained with certain dyes.
C. False – They form an axial stream away from the vessel wall.
D. False – The capillary bed has a greater total cross-sectional area than the venular bed.
E. True – Normal cells, around 7 microns in diameter, become bullet-shaped as they pass through 5 micron diameter capillaries.

4. Coronary blood flow to the left ventricle increases during
a. Early systole
b. Myocardial hypoxia
c. Hypothermia
d. Stimulation of sympathetic nerves to the heart
e. Arterial hypertension
A. False – It falls; coronary vessels are compressed by the contracting myocardium.
B. True – A fall in PO2 has a potent vasodilator effect on coronary vessels. Adenosine released from hypoxic myocardium is also a potent vasodilator.
C. False – The fall in metabolic rate and cardiac output in hypothermia reduce cardiac work and lead to a reduction in coronary blood flow.
D. True – Sympathetic stimulation increases the rate and force of contraction; the resulting increase in the rate of production of vasodilator metabolites dilates coronary vessels.
E. True – Myocardial work and metabolism are increased in hypertension

5. Cortisol
A. Is bound in the plasma to an alpha globulin.
B. Is inactivated in the liver and excreted in the bile.
C. Injections lead to a rise in arterial pressure.
D. Inhibits release of ACTH from the anterior pituitary gland.
E. Is released with a circadian variation so that cortisol blood levels peak in the morning.
A. True – It is bound to transcortin; free cortisol is released to replace that taken up by the tissues.
B. False – The inactive products of cortisol degradation in the liver are conjugated with glucuronic acid and sulphate and excreted in the urine.
C. True – Partly at least because of its mineralocorticoid effects.
D. True – The negative feedback loop that maintains plasma cortisol levels constant.
E. True – It is regulated through a hypothalamic ‘clock’.


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